- More Files
- Specification
Product Description
PLAT (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human PLAT.
Suitable Sample
Cell Culture Supernatant, Milk, Plasma, Serum, Tissue Extract
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Reactivity
Human, Pig
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
- Applications
Quantification
- Gene Info — PLAT
Entrez GeneID
5327Gene Name
PLAT
Gene Alias
DKFZp686I03148, T-PA, TPA
Gene Description
plasminogen activator, tissue
Omim ID
173370Gene Ontology
HyperlinkGene Summary
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
alteplase|plasminogen activator, tissue type|reteplase|t-plasminogen activator|tissue plasminogen activator (t-PA)
- Interactome
- Pathway
- Disease