Matr3 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN309822LP

Matr3 - mouse gene knockout kit via CRISPR, HDR mediated

Functional Cassette: GFP-puro Luciferase-Puro RFP-BSD mBFP-Neo



HDR-mediated knockout kit validation

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Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol Matr3
Locus ID 17184
Components

KN309822G1, Matr3 gRNA vector 1 in pCas-Guide CRISPR vector

KN309822G2, Matr3 gRNA vector 2 in pCas-Guide CRISPR vector

KN309822LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_010771
UniProt ID Q8K310
Synonyms 1110061A14Rik; 2810017I02Rik; AI841759; AW555618; D030046F20Rik; mKIAA0723
Summary May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs (By similarity).[UniProtKB/Swiss-Prot Function]

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