Lamin A (LMNA) Mouse Monoclonal Antibody [Clone ID: OTI3F6]
CAT#: TA803489
LMNA mouse monoclonal antibody, clone OTI3F6 (formerly 3F6)
Size: 30 ul
Formulation: Carrier-Free
Conjugation: Biotin HRP
Specifications
| Product Data | |
| Clone Name | OTI3F6 |
| Applications | IF, WB |
| Recommended Dilution | WB 1:2000 |
| Reactivities | Human, Mouse, Rat |
| Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human LMNA (NP_733821) produced in HEK293T cell. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 74 kDa |
| Gene Name | lamin A/C |
| Database Link | |
| Background | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012] |
| Synonyms | CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
Documents
| Product Manuals |
| FAQs |
|
| SDS |
Resources
| Antibody Resources |
|
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| CF803489 | Carrier-free (BSA/glycerol-free) LMNA mouse monoclonal antibody, clone OTI3F6 (formerly 3F6) | 600,00 EUR | |
| TA803489AM | LMNA mouse monoclonal antibody,clone 3F6, Biotinylated | 509,00 EUR | |
| TA803489BM | LMNA mouse monoclonal antibody,clone 3F6, HRP conjugated | 509,00 EUR | |
| TA803489S | LMNA mouse monoclonal antibody, clone OTI3F6 (formerly 3F6) | 200,00 EUR |