L-SelenoMethionine [3211-76-5]
Katalog-Nummer HY-B1000A-100mg
Size : 100mg
Marke : MedChemExpress
Contact local distributor :
Telefonnummer : +1 850 650 7790
L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase.
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L-SelenoMethionine Chemische Struktur
CAS. Nr. : 3211-76-5
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of L-SelenoMethionine:
- Selenomethionine In-stock
| Beschreibung |
L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase[1][2][3]. |
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| IC50 & Target |
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| In Vitro |
L-SelenoMethionine (1-500 μM; 24-72 h) is selectively inhibits the growth of prostate cancer cells, compared with normal cells[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[2]
Apoptosis Analysis[2]
Cell Cycle Analysis[2]
RT-PCR[3]
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| In Vivo |
L-SelenoMethionine (0.06-12 μg/g diet; p.o. for 3 d) partially or completely prevent the decrease in the serum or plasma levels of total antioxidants in rats exposed to gamma rays, protons or HZE particles[5]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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| Klinische Studie |
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| Molekulargewicht |
196.11 |
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| Formel |
C5H11NO2Se |
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| CAS. Nr. |
3211-76-5 |
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| Appearance |
Solid |
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| Color |
White to off-white |
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| SMILES |
O=C(O)[C@@H](N)CC[Se]C |
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| Structure Classification |
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| Initial Source |
Widespread |
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| Versand | Room temperature in continental US; may vary elsewhere. |
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| Speicherung |
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| Lösungsmittel & Löslichkeit |
In Vitro:
H2O : 14.29 mg/mL (72.87 mM; Need ultrasonic) DMSO : 1 mg/mL (5.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
For the following dissolution methods, please prepare the working solution directly.
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
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| Reinheit & Dokumentation |
Purity: 99.82% |
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| Verweise |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO / H2O | 1 mM | 5.0992 mL | 25.4959 mL | 50.9918 mL | 127.4795 mL |
| 5 mM | 1.0198 mL | 5.0992 mL | 10.1984 mL | 25.4959 mL | |
| H2O | 10 mM | 0.5099 mL | 2.5496 mL | 5.0992 mL | 12.7479 mL |
| 15 mM | 0.3399 mL | 1.6997 mL | 3.3995 mL | 8.4986 mL | |
| 20 mM | 0.2550 mL | 1.2748 mL | 2.5496 mL | 6.3740 mL | |
| 25 mM | 0.2040 mL | 1.0198 mL | 2.0397 mL | 5.0992 mL | |
| 30 mM | 0.1700 mL | 0.8499 mL | 1.6997 mL | 4.2493 mL | |
| 40 mM | 0.1275 mL | 0.6374 mL | 1.2748 mL | 3.1870 mL | |
| 50 mM | 0.1020 mL | 0.5099 mL | 1.0198 mL | 2.5496 mL | |
| 60 mM | 0.0850 mL | 0.4249 mL | 0.8499 mL | 2.1247 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.