Human Calcium independent Phospholipase A2 (PLA2G6) activation kit by CRISPRa
CAT#: GA105547
PLA2G6 CRISPRa kit - CRISPR gene activation of human phospholipase A2 group VI
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Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
| Symbol | PLA2G6 |
| Locus ID | 8398 |
| Kit Components | GA105547G1, Calcium independent Phospholipase A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105547G2, Calcium independent Phospholipase A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105547G3, Calcium independent Phospholipase A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001004426, NM_001199562, NM_003560, NM_001349864, NM_001349865, NM_001349866, NM_001349867, NM_001349868, NM_001349869 |
| UniProt ID | O60733 |
| Synonyms | CaI-PLA2; GVI; INAD1; iPLA2; IPLA2-VIA; iPLA2beta; NBIA2; NBIA2A; NBIA2B; PARK14; PLA2; PNPLA9 |
| Summary | The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010] |
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Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| KN207546 | PLA2G6 - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN207546BN | PLA2G6 - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN207546LP | PLA2G6 - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN207546RB | PLA2G6 - human gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN407546 | PLA2G6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 657,00 EUR |