NG Class
Conventional detergents like DDM, DM, and OG have been indispensable for labs studying membrane
proteins for over 20 years. Now we offer an alternative that could improve protein
structural stability and increase the likelihood of crystallization. The NG class detergents
are modeled after the most popular alkyl glycoside detergents. Architecturally, the
difference lies where the carbon attaches to the ether linkage. The design converts the carbon
from a standard, secondary bonding configuration to a quaternary configuration with two
sugar head groups and two alkyl chains bonded to it.
This distinctive design gives the Anatrace NG detergents unique benefits and characteristics
compared to conventional derivatives like DDM, DM, and OG:
- Lower CMC values
- Increased protein stability after dilution below CMV values
- Stabilization of the first ligand bound GPCR leading to its structure
Katalog-Nummer
Beschreibung
Cond.
H. T. Preis
C998475-100mg
100mg
C998475-10mg
10mg
C998475-50mg
50mg
