Anti-CD74 CE/IVD for IHC - Hematopathology

Anti-CD74 CE/IVD for IHC - Hematopathology


Cluster of Differentiation 74 (CD74), also known as the MHC Class II-associated invariant chain (II), is a type II transmembrane protein. In normal tissues, CD74 is expressed in B cells, monocytes, macrophages, Langerhans cells, dendritic cells, subsets of activated T cells, and thymic epithelium. Under inflammatory conditions, CD74 expression may be observed in endothelial and certain epithelial cells. CD74 expression has been observed in ~90% of B-cell cancers evaluated, as well as the majority of cell lines derived from these cancers. CD74 is a marker for distinguishing atypical fibroxanthoma from malignant fibrous histiocytoma, and Small Cell Lung Carcinoma (SCLC) from Non-Small Cell Lung Carcinoma (NSCLC). It is also a useful marker for distinguishing leiomyosarcoma from leiomyoma. CD74 is clinically indicated as a marker for germinal center lymphocytes and B-cell lymphomas.




 Tonsil section
Tonsil section

Katalog-Nummer
Beschreibung
Cond.
H. T. Preis
CD74; Clone LN2 (Ready-To-Use)
A00048-0002
 2ml 
CD74; Clone LN2 (Ready-To-Use)
A00048-0007
 7ml 
CD74; Clone LN2 (Ready-To-Use)
A00048-0025
 25ml