Human Glycerol kinase (GK) activation kit by CRISPRa

CAT#: GA101812

GK CRISPRa kit - CRISPR gene activation of human glycerol kinase



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol GK
Locus ID 2710
Kit Components

GA101812G1, Glycerol kinase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101812G2, Glycerol kinase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101812G3, Glycerol kinase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000167, NM_001128127, NM_001205019, NM_203391
UniProt ID P32189
Synonyms GK1; GKD
Summary The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

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