Human Glucosidase 2 subunit beta (PRKCSH) activation kit by CRISPRa

CAT#: GA103779

PRKCSH CRISPRa kit - CRISPR gene activation of human protein kinase C substrate 80K-H



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PRKCSH
Locus ID 5589
Kit Components

GA103779G1, Glucosidase 2 subunit beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103779G2, Glucosidase 2 subunit beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103779G3, Glucosidase 2 subunit beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001001329, NM_001289102, NM_001289103, NM_001289104, NM_002743
UniProt ID P14314
Synonyms AGE-R2; G19P1; GIIB; PCLD; PCLD1; PKCSH; PLD1; VASAP-60
Summary This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

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