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> Products for research > Immunoassays > ELISA kits and sets > Fish > Fish Glucosamine-Fructose-6-Phosphate Aminotransferase [isomerizing] 1 (GFPT1) ELISA Kit

Fish Glucosamine-Fructose-6-Phosphate Aminotransferase [isomerizing] 1 (GFPT1) ELISA Kit

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Katalog-Nummer MBS9901217

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Fish Glucosamine-Fructose-6-Phosphate Aminotransferase [isomerizing] 1 (GFPT1) ELISA Kit

Product Gene Name

GFPT1 elisa kit

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
Request Current Manual
OMIM
M90516 mRNA
3D Structure
ModBase 3D Structure for Q06210
Species Reactivity
Fish
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Other Notes
Small volumes of GFPT1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for GFPT1 purchase
MBS9901217 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glucosamine-Fructose-6-Phosphate Aminotransferase [isomerizing] 1 (GFPT1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GFPT1. The ELISA analytical biochemical technique of the MBS9901217 kit is based on GFPT1 antibody-GFPT1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GFPT1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GFPT1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GFPT1. It may not necessarily be applicable to this product.
NCBI GI #
205277386
NCBI GeneID
2673
NCBI Accession #
NP_002047.2
NCBI GenBank Nucleotide #
NM_002056.3
UniProt Primary Accession #
Q06210
UniProt Secondary Accession #
Q53QE6; Q9BXF8
UniProt Related Accession #
Q06210
Molecular Weight
76,759 Da
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NCBI Official Full Name
glutamine--fructose-6-phosphate aminotransferase
NCBI Official Synonym Full Names
glutamine--fructose-6-phosphate transaminase 1
NCBI Official Symbol
GFPT1  
NCBI Official Synonym Symbols
GFA; GFAT; GFPT; MSLG; CMS12; GFAT1; CMSTA1; GFAT 1; GFAT1m; GFPT1L
  
NCBI Protein Information
glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
UniProt Protein Name
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
UniProt Synonym Protein Names
D-fructose-6-phosphate amidotransferase 1; Glutamine:fructose-6-phosphate amidotransferase 1; GFAT 1; GFAT1; Hexosephosphate aminotransferase 1
Protein Family
Glutamine--fructose-6-phosphate aminotransferase
UniProt Gene Name
GFPT1  
UniProt Synonym Gene Names
GFAT; GFPT; GFAT 1; GFAT1  
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NCBI Summary for GFPT1
This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq, Sep 2008]
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UniProt Comments for GFPT1
GFAT: Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Homotetramer (Potential). Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 2.6.1.16; Transferase

Chromosomal Location of Human Ortholog: 2p13.3

Cellular Component: cytosol; extracellular exosome

Molecular Function: glutamine-fructose-6-phosphate transaminase (isomerizing) activity

Biological Process: circadian regulation of gene expression; energy reserve metabolic process; fructose 6-phosphate metabolic process; glutamine metabolic process; IRE1-mediated unfolded protein response; protein N-linked glycosylation; UDP-N-acetylglucosamine biosynthetic process; UDP-N-acetylglucosamine metabolic process

Disease: Myasthenic Syndrome, Congenital, Associated With Acetylcholine Receptor Deficiency; Myasthenic Syndrome, Congenital, With Tubular Aggregates 1
Research Articles on GFPT1
1. High GFAT1 expression is associated with hepatocellular carcinoma.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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