General Info
Host: | Rabbit |
Applications: | WB/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Proto-oncogene vav (131-180 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000ELISA 1:5000IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | VAV1 |
Gene ID: | 7409 |
Uniprot ID: | VAV_HUMAN |
Immunogen Region: | 131-180 aa |
Specificity: | VAV1 Polyclonal Antibody detects endogenous levels of VAV1 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human VAV1 at the amino acid range 131-180 |
Description
Post Translational Modifications | Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN. |
Function | Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. |
Protein Name | Proto-Oncogene Vav |
Database Links | Reactome: R-HSA-114604Reactome: R-HSA-1257604Reactome: R-HSA-1433557Reactome: R-HSA-193648Reactome: R-HSA-2029482Reactome: R-HSA-2219530Reactome: R-HSA-2871796Reactome: R-HSA-2871809Reactome: R-HSA-389359Reactome: R-HSA-416482Reactome: R-HSA-4420097Reactome: R-HSA-512988Reactome: R-HSA-5218920Reactome: R-HSA-6811558Reactome: R-HSA-8980692Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013408Reactome: R-HSA-9027284Reactome: R-HSA-912631Reactome: R-HSA-9664422Reactome: R-HSA-9679191Reactome: R-HSA-9748787Reactome: R-HSA-983695 |
Alternative Antibody Names | Anti-Proto-Oncogene Vav antibodyAnti-VAV1 antibodyAnti-VAV antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance