Reagents and instruments for immunology, cell biology and molecular biology.
 
> Anti-HTR4 antibody (40-120 N-Term)

Anti-HTR4 antibody (40-120 N-Term)

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Cat# NB-22-5766-200ul

Size : 200µg

Brand : Neo Biotech

Contact local distributor :


Phone : +1 850 650 7790

  • Western blot analysis of the lysates from 293 cells using Collagen I Alpha 2 antibody.
  • Immunofluorescence analysis of HeLa cells, using 5-HT-4 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from Jurkat/COLO205, using 5-HT-4 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using SR-4 Polyclonal Antibody

General Info

Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-5-hydroxytryptamine receptor 4 (21-70 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol: HTR4
Gene ID: 3360
Uniprot ID: 5HT4R_HUMAN
Immunogen Region: 21-70 aa
Specificity: SR-4 Polyclonal Antibody detects endogenous levels of SR-4 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human 5-HT-4 at the amino acid range 21-70

Description

Function This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
Protein Name 5-Hydroxytryptamine Receptor 4
5-Ht-4
5-Ht4
Serotonin Receptor 4
Database Links Reactome: R-HSA-390666
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Endosome
Interaction With Snx27 Mediates Recruitment To Early Endosomes
While Interaction With Nherf1 And Ezr Might Target The Protein To Specialized Subcellular Regions
Such As Microvilli
Alternative Antibody Names Anti-5-Hydroxytryptamine Receptor 4 antibody
Anti-5-Ht-4 antibody
Anti-5-Ht4 antibody
Anti-Serotonin Receptor 4 antibody
Anti-HTR4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance