Reagents and instruments for immunology, cell biology and molecular biology.
 
> Anti-Phospho-IL7R-Tyr449 antibody (380-460)

Anti-Phospho-IL7R-Tyr449 antibody (380-460)

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Cat# NB-22-0721-200ul

Size : 200µg

Brand : Neo Biotech

Contact local distributor :


Phone : +1 850 650 7790

  • Western blot analysis of lysates from COLO205 cells, using IL-7R/CD127 (Phospho-Tyr449) Antibody. The lane on the right is blocked with the phospho peptide.
  • Immunofluorescence analysis of HUVEC cells, using IL-7R/CD127 (Phospho-Tyr449) Antibody. The picture on the right is blocked with the phospho peptide.

General Info

Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Interleukin-7 receptor subunit alpha-Tyr449 (410-459 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol: IL7R
Gene ID: 3575
Uniprot ID: IL7RA_HUMAN
Immunogen Region: 410-459 aa
Specificity: Phospho-IL-7R (Y449) Polyclonal Antibody detects endogenous levels of IL-7R protein only when phosphorylated at Y449.
Immunogen: The antiserum was produced against synthesized peptide derived from the human IL-7R/CD127 around the phosphorylation site of Tyr449 at the amino acid range 410-459

Description

Function Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
Protein Name Interleukin-7 Receptor Subunit Alpha
Il-7 Receptor Subunit Alpha
Il-7r Subunit Alpha
Il-7r-Alpha
Il-7ra
Cdw127
Cd Antigen Cd127
Database Links Reactome: R-HSA-1266695
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Membrane
Isoform 4: Secreted
Alternative Antibody Names Anti-Interleukin-7 Receptor Subunit Alpha antibody
Anti-Il-7 Receptor Subunit Alpha antibody
Anti-Il-7r Subunit Alpha antibody
Anti-Il-7r-Alpha antibody
Anti-Il-7ra antibody
Anti-Cdw127 antibody
Anti-Cd Antigen Cd127 antibody
Anti-IL7R antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance