General Info
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Phospho-GRB2-associated-binding protein 1-Tyr627 (611-643 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | GAB1 |
| Gene ID: | 2549 |
| Uniprot ID: | GAB1_HUMAN |
| Immunogen Region: | 611-643 aa |
| Specificity: | Phospho-Gab 1 (Y627) Polyclonal Antibody detects endogenous levels of Gab 1 protein only when phosphorylated at Y627. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GAB1 around the phosphorylation site of Tyr627 at the amino acid range 611-643 |
Description
| Function | Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway. |
| Protein Name | Grb2-Associated-Binding Protein 1Grb2-Associated Binder 1Growth Factor Receptor Bound Protein 2-Associated Protein 1 |
| Database Links | Reactome: R-HSA-109704Reactome: R-HSA-1236382Reactome: R-HSA-1257604Reactome: R-HSA-180292Reactome: R-HSA-1963642Reactome: R-HSA-2219530Reactome: R-HSA-5637810Reactome: R-HSA-5654689Reactome: R-HSA-5654695Reactome: R-HSA-5654710Reactome: R-HSA-5654720Reactome: R-HSA-5655253Reactome: R-HSA-5655291Reactome: R-HSA-5655302Reactome: R-HSA-5655332Reactome: R-HSA-6811558Reactome: R-HSA-8851907Reactome: R-HSA-8853659Reactome: R-HSA-8865999Reactome: R-HSA-8875555Reactome: R-HSA-8875656Reactome: R-HSA-9027276Reactome: R-HSA-9028335Reactome: R-HSA-9664565Reactome: R-HSA-9665348 |
| Alternative Antibody Names | Anti-Grb2-Associated-Binding Protein 1 antibodyAnti-Grb2-Associated Binder 1 antibodyAnti-Growth Factor Receptor Bound Protein 2-Associated Protein 1 antibodyAnti-GAB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance