General Info
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Endophilin-A1 (30-110 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | SH3GL2 |
Gene ID: | 6456 |
Uniprot ID: | SH3G2_HUMAN |
Immunogen Region: | 30-110 aa |
Specificity: | Endophilin I Polyclonal Antibody detects endogenous levels of Endophilin I protein. |
Immunogen: | Synthesized peptide derived from Endophilin I at the amino acid range 30-110 |
Description
Function | Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes. |
Protein Name | Endophilin-A1Een-B1Endophilin-1Sh3 Domain Protein 2aSh3 Domain-Containing Grb2-Like Protein 2 |
Database Links | Reactome: R-HSA-177504Reactome: R-HSA-182971Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722Reactome: R-HSA-437239Reactome: R-HSA-6807004Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8875360 |
Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinEarly EndosomePresynapse |
Alternative Antibody Names | Anti-Endophilin-A1 antibodyAnti-Een-B1 antibodyAnti-Endophilin-1 antibodyAnti-Sh3 Domain Protein 2a antibodyAnti-Sh3 Domain-Containing Grb2-Like Protein 2 antibodyAnti-SH3GL2 antibodyAnti-CNSA2 antibodyAnti-SH3D2A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance