General Info
| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Chondroitin sulfate synthase 1 (341-390 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | CHSY1 |
| Gene ID: | 22856 |
| Uniprot ID: | CHSS1_HUMAN |
| Immunogen Region: | 341-390 aa |
| Specificity: | CHSY1 Polyclonal Antibody detects endogenous levels of CHSY1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CHSY1 at the amino acid range 341-390 |
Description
| Function | Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling. |
| Protein Name | Chondroitin Sulfate Synthase 1Chondroitin Glucuronyltransferase 1Chondroitin Synthase 1Chsy-1Glucuronosyl-N-Acetylgalactosaminyl-Proteoglycan 4-Beta-N-Acetylgalactosaminyltransferase 1N-Acetylgalactosaminyl-Proteoglycan 3-Beta-Glucuronosyltransferase 1N-Acetylgalactosaminyltransferase 1 |
| Database Links | Reactome: R-HSA-2022870Reactome: R-HSA-3595177 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinSecreted |
| Alternative Antibody Names | Anti-Chondroitin Sulfate Synthase 1 antibodyAnti-Chondroitin Glucuronyltransferase 1 antibodyAnti-Chondroitin Synthase 1 antibodyAnti-Chsy-1 antibodyAnti-Glucuronosyl-N-Acetylgalactosaminyl-Proteoglycan 4-Beta-N-Acetylgalactosaminyltransferase 1 antibodyAnti-N-Acetylgalactosaminyl-Proteoglycan 3-Beta-Glucuronosyltransferase 1 antibodyAnti-N-Acetylgalactosaminyltransferase 1 antibodyAnti-CHSY1 antibodyAnti-CHSY antibodyAnti-CSS1 antibodyAnti-KIAA0990 antibodyAnti-UNQ756 antibodyAnti-PRO1487 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance