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Reagents and instruments for immunology, cell biology and molecular biology.

Anti-TFAP2C antibody (370-450 C-Term)

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Cat# NB-22-1618-200ul

Size : 200µg

Contact local distributor :

Phone : +1 850 650 7790

Brand : Neo Biotech

Contact local distributor :

Phone : +1 850 650 7790

Western blot analysis of lysates from HepG2 and HUVEC cells, using AP2C Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from K562 cells using AP2C antibody.
Immunohistochemical analysis of paraffin-embedded Human breast. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
Immunohistochemical analysis of paraffin-embedded Human breast. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
Immunohistochemical analysis of paraffin-embedded Human breast. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
Western blot analysis of various cells using AP-2 Gamma Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

General Info

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Transcription factor AP-2 gamma (401-450 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol:	TFAP2C
Gene ID:	7022
Uniprot ID:	AP2C_HUMAN
Immunogen Region:	401-450 aa
Specificity:	AP-2 Gamma Polyclonal Antibody detects endogenous levels of AP-2 Gamma protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human AP2C at the amino acid range 401-450

Description

Function	Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Protein Name	Transcription Factor Ap-2 Gamma Ap2-Gamma Activating Enhancer-Binding Protein 2 Gamma Transcription Factor Erf-1
Database Links	Reactome: R-HSA-3232118 Reactome: R-HSA-8866904 Reactome: R-HSA-8866906 Reactome: R-HSA-8866907 Reactome: R-HSA-8866910 Reactome: R-HSA-8866911 Reactome: R-HSA-9827857
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Transcription Factor Ap-2 Gamma antibody Anti-Ap2-Gamma antibody Anti-Activating Enhancer-Binding Protein 2 Gamma antibody Anti-Transcription Factor Erf-1 antibody Anti-TFAP2C antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance