Vitamin B12 [68-19-9]

Cat# HY-B0315-500mg

Size : 500mg

Brand : MedChemExpress

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Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood.

For research use only. We do not sell to patients.

Vitamin B12 Chemical Structure

CAS No. : 68-19-9

*

This product is a controlled substance and not for sale in your territory.

  • Journal of Pharmaceutical Investigation. 2021 Mar 31.
  • Journal of Pharmaceutical Investigation. 2021 Apr.
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood.

Human Endogenous Metabolite

 

Microbial Metabolite

 

In Vitro

Vitamin B12 is one of the eight B vitamins. It is normally involved in the metabolism of every cell of the human body, especially affecting DNA synthesis and regulation, but also fatty acid synthesis (especially odd chain fatty acids) and energy production. However, many (though not all) of the effects of functions of B12 can be replaced by sufficient quantities of folic acid (vitamin B9), since B12 is used to regenerate folate in the body. Most vitamin B12 deficiency symptoms are actually folate deficiency symptoms, since they include all the effects of pernicious anemia and megaloblastosis, which are due to poor synthesis of DNA when the body does not have a proper supply of folic acid for the production of thymine due to methyl trapping. When sufficient folic acid is available, all known B12 related deficiency syndromes normalize, save those narrowly connected with the vitamin B12-dependent enzymes Methylmalonyl Coenzyme A mutase, and 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), also known as methionine synthase; and the buildup of their respective substrates (methylmalonic acid, MMA) and homocysteine.Coenzyme B12's reactive C-Co bond participates in three main types of enzyme-catalyzed reactions.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

  • [1]. http://en.wikipedia.org/wiki/Vitamin_B12

    [2]. Banerjee, R. and S.W. Ragsdale, The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes. Annu Rev Biochem, 2003. 72: p. 209-47.  [Content Brief]

  • [1]. http://en.wikipedia.org/wiki/Vitamin_B12

    [2]. Banerjee, R. and S.W. Ragsdale, The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes. Annu Rev Biochem, 2003. 72: p. 209-47.

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 years; -20°C, 6 months (protect from light). When stored at -80°C, please use it within 1 years. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 0.7378 mL 3.6890 mL 7.3781 mL 18.4451 mL
DMSO 5 mM 0.1476 mL 0.7378 mL 1.4756 mL 3.6890 mL
10 mM 0.0738 mL 0.3689 mL 0.7378 mL 1.8445 mL
15 mM 0.0492 mL 0.2459 mL 0.4919 mL 1.2297 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Metabolic Enzyme/Protease
  • Endogenous Metabolite
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Keywords:

Vitamin B1268-19-9CyanocobalaminVitamin B 12Vitamin B-12Endogenous MetaboliteInhibitorinhibitorinhibit

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