Tumor Necrosis Factor-alpha; human TNF-α

Cat# RC214-12-10ug

Size : 10ug

Brand : Bio Basic

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TNF alpha, Tumor Necrosis Factor-alpha, human
Storage: (-15 to -20)C
Product Description: TNF alpha, Tumor Necrosis Factor-alpha, human: Tumor necrosis factor alpha (TNF-α), also called cachectin, is produced by neutrophils, activated lymphocytes, macrophages, NK cells, LAK cells, astrocytes endothelial cells, smooth muscle cells and some transformed cells. TNF-α occurs as a secreted, soluble form and as a membrane-anchored form, both of which are biologically active. The naturally-occurring form of TNF-α is glycosylated, but non-glycosylated recombinant TNF-α has comparable biological activity. The biologically active native form of TNF-α is reportedly a trimer. Human and murine TNF-α show approximately 79% homology at the amino acid level and crossreactivity between the two species. Two types of receptors for TNF-α have been described and virtually all cell types studied show the presence of one or both of these receptor types., Accession number: NM_000594, UnitProt ID: P01375
Total Product Size:
RC214-12 (10ug)
RC214-12 (50ug)
RC214-12 (1mg)
Number of Containers: 1
Refrigeration Requirements: Freezer
Shipping Conditions: ICE
UNSPSC Code: 41116127
UNSPSC Category: Other Cytokines and Chemokines
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