Biotrend > TP53 mouse monoclonal antibody, clone DO-1, HRP conjugated
TP53 mouse monoclonal antibody, clone DO-1, HRP conjugated
Cat# TA804804BM
Size : 100ul
Request more information
Please log in to use this feature.
Contact local distributor :
p53 (TP53) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: DO-1]
SKU
TA804804BM
TP53 mouse monoclonal antibody, clone DO-1, HRP conjugated
| Product Data | |
| Clone Name | DO-1 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Recombinant human wild type p53 protein expressed in E. coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | tumor protein p53 |
| Database Link | |
| Background | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013] |
| Synonyms | BCC7; LFS1; P53; TRP53 |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Amyotrophic lateral sclerosis (ALS), Apoptosis, Basal cell carcinoma, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, Glioma, Huntington's disease, MAPK signaling pathway, Melanoma, Neurotrophin signaling pathway, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer, Thyroid cancer, Wnt signaling pathway |
| Product Manuals |
| FAQs |
|
| SDS |
| Antibody Resources |
|
| SKU | Description | Size | ||
|---|---|---|---|---|
| CF804804 | Carrier-free (BSA/glycerol-free) TP53 mouse monoclonal antibody, clone DO-1 | 100 ug | | |
| TA804804 | TP53 mouse monoclonal antibody, clone DO-1 | 100 ul | | |
| TA804804AM | TP53 mouse monoclonal antibody, clone DO-1, Biotinylated | 100 ul | | |
| TA804804S | TP53 mouse monoclonal antibody, clone DO-1 | 30 ul | | |