Strigolactone GR24 (rac-GR24)

Strigolactone GR24 is a natural product that belongs to the class of sesquiterpene lactones. It has been found to have a wide range of biological activities, including anti-inflammatory effects and inhibition of energy metabolism in 3T3-L1 preadipocytes. Strigolactone GR24 has also been shown to inhibit the proliferation of cancer cells by affecting the polymerase chain reaction (PCR) process. This compound has been shown to have chemo-preventive properties against bowel disease in animal models. In addition, it is an inhibitor of histological analysis in rats with induced colitis. Strigolactone GR24 has also been found to inhibit DNA synthesis in rat hepatoma cells, which may be due to its ability to bind tightly with DNA. This natural product can be used as a model system for studying transfer reactions and molecular docking analysis.

[3E(R*),3aα,8bα]-(±)-3-[[(2,5-Dihydro-4-methyl-5-oxo-2-furanyl)oxy]methylene]-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one; rel-(3E,3aR,8bS)-3-[[[(2R)-2,5-Dihydro-4-methyl-5-oxo-2-furanyl]oxy]methylene]-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one; [3E(R*),3aα,8bα]-3-[[(2,5-Dihydro-4-methyl-5-oxo-2-furanyl)oxy]methylene]-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one; GR 24; rac-GR24

76974-79-3

C₁₇H₁₄O₅

298.29

≥98%

White to off-white powder

Conforms to reference

154-155°C (lit)

May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

 All products should be handled by qualified personnel only, trained in laboratory procedures.