Specifications

Product Data
Applications	FC, IF, IHC, WB
Recommended Dilution	WB: 1:1000, IHC: 1:10~50, IF: 1:10~50, FC: 1:10~50
Reactivities	Human (Predicted: Mouse, Zebrafish, Chicken, Xenopus)
Host	Rabbit
Isotype	Ig
Clonality	Polyclonal
Immunogen	This SOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-119 amino acids from the N-terminal region of human SOX2.
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Predicted Protein Size	34310 Da
Gene Name	SRY-box 2
Database Link	NP_003097 Entrez Gene 20674 MouseEntrez Gene 6657 Human UniProt ID P48431
Background	The intronless gene for SOX2 encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.
Synonyms	ANOP3; MCOPS3
Reference Data
Protein Families	Adult stem cells, Cancer stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors