Specifications

Product Data
Clone Name	S29-29
Applications	WB
Reactivities	Mouse, Rat
Host	Mouse
Isotype	IgG1
Clonality	Monoclonal
Immunogen	Fusion protein amino acids 501-582 (cytoplasmic C-terminus) of rat VGlut2.
Formulation	PBS pH7.4, 50% glycerol
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Gene Name	solute carrier family 17 member 6
Database Link	NP_445879 Entrez Gene 140919 MouseEntrez Gene 84487 Rat UniProt ID Q9JI12
Background	The ATP-dependent, chloride-sensitive vesicular glutamate transporters (VGLUT) include BNPI (VGLUT1),VGLUT2 (DNPI) and VGLUT3. The brain expresses BNPI (brain specific Na+-dependent inorganic phosphate (Pi) cotransporter) and VGLUT2 in a complementary fashion. The telencephalic regions express BNPI, whereas the lower brainstem and diencephalic regions express VLGUT2. Rat pinealocytes express both BNPI andVGLUT2. The striatum, hippocampus, cerebral cortex and raphe nuclei express VGLUT3 in a small number ofneurons. Pancreatic and cells express BNPI and VGLUT2 in response to glucose concentrations. Human VGLUT3 shares a 72% sequence homology with VLGUT2 and BNPI.
Synonyms	DNPI; VGLUT2
Note	Detects ~60kDa.
Reference Data