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> Skyrin [602-06-2]

Skyrin [602-06-2]

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Cat# HY-119739

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Brand : MedChemExpress

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Skyrin is an anthraquinone compound that can be isolated from almond fruit. Skyrin is a receptor-selective glucagon antagonist. Skyrin can inhibit the growth of tumor cells.

For research use only. We do not sell to patients.

Skyrin Chemical Structure

Skyrin Chemical Structure

CAS No. : 602-06-2

This product is a controlled substance and not for sale in your territory.

Description

Skyrin is an anthraquinone compound that can be isolated from almond fruit. Skyrin is a receptor-selective glucagon antagonist. Skyrin can inhibit the growth of tumor cells[1][2].

Molecular Weight

538.46

Formula

C30H18O10
CAS No.

602-06-2
SMILES

CC1=CC(O)=C2C(C(C3=C(C2=O)C(O)=CC(O)=C3C4=C(C=C(C(C(C5=C6C=C(C=C5O)C)=O)=C4C6=O)O)O)=O)=C1
Structure Classification
  • Quinones
  • Anthraquinones
Initial Source
  • Plants
  • Rhamnaceae
  • Ventilago leiocarpa Benth.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References

  • [1]. Parker JC, et al. Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes. Diabetes. 2000 Dec;49(12):2079-86.  [Content Brief]

    [2]. Lin LC, et al. Cytotoxic principles from Ventilago leiocarpa. J Nat Prod. 2001 May;64(5):674-6.  [Content Brief]

  • [1]. Parker JC, et al. Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes. Diabetes. 2000 Dec;49(12):2079-86.

    [2]. Lin LC, et al. Cytotoxic principles from Ventilago leiocarpa. J Nat Prod. 2001 May;64(5):674-6.

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Skyrin Related Classifications

  • GPCR/G Protein
  • GCGR

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Skyrin602-06-2GCGRGlucagon ReceptorGlucagon receptorAntagonistAntitumorInhibitorinhibitorinhibit