ROR1 (NM_005012) Human Tagged Lenti ORF Clone
CAT#: RC214967L3
- LentiORF®
Lenti ORF clone of Human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1, Myc-DDK-tagged
Product Images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Symbol | ROR1 |
| Synonyms | dJ537F10.1; NTRKR1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data | The ORF insert of this clone is exactly the same as(RC214967). |
| Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
| ACCN | NM_005012 |
| ORF Size | 2811 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at info@biotrend.com The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005012.1 |
| RefSeq Size | 3358 bp |
| RefSeq ORF | 2814 bp |
| Locus ID | 4919 |
| UniProt ID | Q01973 |
| Cytogenetics | 1p31.3 |
| Domains | KR, FRI, pkinase, TyrKc, S_TKc, ig, IGc2, IG |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| MW | 104.1 kDa |
| Gene Summary | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012] |
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Resources
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| RC214967 | ROR1 (Myc-DDK-tagged)-Human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1 | 1 287,00 EUR | |
| RC214967L1 | Lenti ORF clone of Human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1, Myc-DDK-tagged | 1 587,00 EUR | |
| RC214967L2 | Lenti ORF clone of Human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1, mGFP tagged | 1 587,00 EUR | |
| RC214967L4 | Lenti ORF clone of Human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1, mGFP tagged | 1 587,00 EUR | |
| RC600058 | ROR1 (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens receptor tyrosine kinase-like orphan receptor 1, transcript variant 1, Signal peptide (1-29) plus EC domain (30-406) | 457,00 EUR | |
| RG214967 | ROR1 (tGFP-tagged) - Human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1 | 1 487,00 EUR | |
| SC117005 | ROR1 (untagged)-Human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1 | 1 288,00 EUR |