RET Antibody (Phospho-Tyr1015)
Cat# OASG06336
Size : 100ul
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
RET Antibody (Phospho-Tyr1015) (OASG06336)
| Datasheets/Manuals | Printable datasheet for anti-RET (OASG06336) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Monkey |
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| Product Format | Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | IHC, WB |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | Synthesized peptide derived from human Ret around the phosphorylation site of Y1015. Location: 960-1040aa. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Target Post-Translational Modification | Phospho-Tyr1015 |
| Specificity | Phospho-Ret (Tyr1015) Polyclonal Antibody detects endogenous levels of Ret protein only when phosphorylated at Y1015. |
| Application Info | WB 1:500-1:2000; ELISA 1:5000; |
| Gene Symbol | RET |
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| Gene Full Name | ret proto-oncogene |
| Alias Symbols | PTC, MTC1, HSCR1, MEN2A, MEN2B, CDHF12, CDHR16, RET-ELE1 |
| NCBI Gene Id | 5979; 19713; |
| Description of Target | This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. |
| Uniprot ID | P07949, P35546 |
| Molecular Weight | 124 kDa |
