Red Blood Cells Mouse Monoclonal Antibody [Clone ID: 34-3C]
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Specifications
Product Data | |
Clone Name | 34-3C |
Applications | FN |
Recommended Dilution | Flow Cytometry (Ref.2,3): The typical starting working dilution is 1/50. Functional Assays (Ref.1,2,4,5). Positive control: Mouse erythrocytes. |
Reactivities | Mouse |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | RBC |
Specificity | The monoclonal antibody 34-3C recognizes an exposed surface determinant of intact red blood cells (RBC). The high-affinity anti-RBC monoclonal antibody efficiently bind to Fc receptors on macrophages inducing anemia in vivo due to a rapid Fc receptor (FcyR)-mediated erythrophagocytosis of opsonised RBC in spleen and livers. The capacity of the antibody to interact with FcyR is responsible for its haemolytic activity |
Formulation | PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% BSA |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Synonyms | RBCs, RBC |
Reference Data |
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