Rb1cc1 (NM_009826) Mouse Tagged ORF Clone
CAT#: MR216914
- TrueORF®
Rb1cc1 (Myc-DDK-tagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1)
ORF Plasmid: tGFP
Lentiviral Particles: DDK w/ Puro mGFP w/ Puro
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Product Images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Symbol | Rb1cc1 |
| Synonyms | 2900055E04Rik; 5930404L04Rik; Cc1; FIP200; LaXp180 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | >MR216914 ORF sequence Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGTTATATGTGTTTCTGGTTAACACCGGAACCACGCTGACATTTGACACTGAGCTAACTGTGCAAA CTGTGGCTGATCTTAAGCATGCCATTCAAAGCAAATACAAGATTGCTATTCAGCACCAGGTTCTGGTGGT CAATGGAGGAGAATGCATGGCTGCAGATCGAAGAGTGTGTACTTACAGCGCTGGGACGGACACAAATCCA ATTTTTCTTTTTAATAAAGAAATGATCTTATGTGACCGTGCACCTGCTATTCCTAAAGCTACCTTTTCAA CAGAAAATGACATGGAAATAAAAGTTGAAGAGTCTCTTATGATGCCTGCAGTTTTCCACACTGTTGCTTC AAGGACACAGCTTGCAGTGGAAATGTATGACGTTGCCAAGAAGCTCTGCTCTTTCTGTGAAGGGCTTGTC CATGATGAACATCTTCAGCACCAAGGCTGGGCTGCAATCATGGCCAATCTGGAGGACTGTTCAAATTCAT ACCAAAAACTTCTTTTCAAGTTTGAAAGTATTTATTCTGATTATCTTCAATCCATAGAAGACATCAAGTT AAAACTTACTCATTTAGGAACTGCTGTTTCAGTAATGGCCAAGATTCCACTATTGGAGTGCCTAACCAGA CATAGTTACAGGGAATGTTTGGGAAGACCGGATTCTTTGAATGAACATGAAGGCTCAGAGAAAGCTGAGA TGAAAAGATCTACTGAATTGGTGCTCTCTCCTGATATGCCTAGAACATCGAACACATCCTTGGTAACCTC ATTTCACAAGTCAATGGAGCATGTAGCTCCAGATCCCACCGGTACTGAACGTGGCAAAGAACTTAGGGAA TCTTGTCAAAGTACTGTCCAGCAAGAAGAAGCTTCAGTGGATGCTAAAGACAGTGATCTGCCTTTTTTTA ATGTTTCTTTGTTAGACTGGATAAATGTTCAAGATAGACCCAATGATGTGGAATCTCTGGTCAGGAAGTG CTTTGATTCTATGAGCAGGCTTGACCCAAAGATTATTCAACCATTTATGTTAGAATGCCATCAAACTATT GCCAAACTTGATAATCAGAATATGAAAGCCATTAAAGGGCTTGAAGATCGGCTGTATGCCTTGGACCAGA TGATTGCTAGCTGTAGCCGGCTGGTAAATGAACAGAAAGAGCTTGCTCAGGGATTTTTAGCTAATCAGAT GAGAGCTGAAAACTTGAAGGATGCATCTGTGTTACCTGATCTGTGTCTGAGTCATGCAAATCAACTAATG ATTATGTTGCAAAACCACAGAAAACTGTTGGATATTAAACAGAAGTGCACCACTGCCAAACAAGAGCTAG CAAACAATCTCCACGTCAGACTGAAGTGGTGTTGTTTTGTGATGCTTCATGCTGATCAAGATGGAGAAAA ACTGCAGGCACTGCTCCGCCTTGTAATAGAGCTGTTAGAAAGAGTCAGAATTGTTGAGGCTCTTAGTACA GTTCCTCAGATGTATTGCCTAGCTGTTGTTGAGGTTGTAAGAAGAAAAATGTTCATTAAACACTACAGAG AGTGGGCTGGTGCTTTAGTCAAAGACGGAAAACAACTATATGAAGCTGAAAAGTCAAAAAGGGAATCCTT TGGGAAATTATTTAGGAAGTCCTTTTTAAGAAATCGTCTGTTTAAAGGACTGGACTCCTGGCCTTCCTCA TTTTGTACTCAGAAGCCTCGAAAATTTGACTGTGAACTTCCAGATATATCGTTAAAAGATTTACAGTTTC TTCAATCATTTTGTCCTTCAGAAGTGCAGCCATTCCTCAGGGTCCCCTTACTTTGTGACTTTGAACCTCT ACACCAGCATGTACTTGCCCTACATAATTTGGTAAAAGCAGCACAAAGTTTGGATGAAATGTCACAGACT ATTACAGATCTCCTAAATGAACAAAAGGTATCCACAAGTCAGGCATCCCCACAGTCAGCTGCTTCTCCAA GAATAGAAAGTACAACAGGCATTACAACCACTACCTCACCAAAAACTCCTCCTCCACTAACTGTTCAGGA CACCTTATGTCCGGCAGTGTGTCCCTTAGAAGAATTATCTCCAGATAGTATCGATGCTCATACATTTGAT TTTGAAACCATCTCCCATCCAAACACAGAACAACCTGTTCACCAAGCTTCTATAGACTTGGATTCATTAG CAGAAAGCCCTGAGTCTGACTTTATGTCTGCTGTGAATGAGTTTGTGATAGAAGAAAATTTATCGTCTCC AAACCCTATAAGTGATCCACAAAGTCCAGAAATGATGGTGGAGTCACTTTACTCTTCAGTCATCAATGCA ATAGATAGTAGGCGTATGCAAGACACAAGTACACGTGGAAACGAGGGCTTTGGGGATCGGGCTGCTCTAC ATGTCCAGCTGGAGAAATGCAGAGCTGCTGCACAAGACTCTCACAGCAGTATACAAACCATCAAGGACGA TCTGTGCCATTTCAGAACATTTGTACAAAAAGAACAGTGTGACTTAGCAAATTATTTAAAATGTACAGCT GTAGAAATAAGAAATATTATTGAAAAAGTAAAATGTTCTCTAGAAATAACACTAAAGGAAAAGCATCAGC AAGAACTCCAATCTTTAAAAATTGAGTATGAATGTAAACTTGATGCTCTAGTAAAAGACAGTGAAGAAAA TGTAAATAAAATTTTAAAATTGAAAGAAAATTTAGTATCCCTTGAAGAGGCTTTACAAAATAAAGACAAT GAATTCACTTCGATTAAACATGAAAAGGATGCTATTGTCTGTGTGCAGCAAGAAAAGGATCAGAAGTTGT TAGAGATGGAAAAGATAATGCATACTCAACATTGTGAAATTAAAGAACTGAAGCAGTCACGAGAGATGGC ATTAGAAGACCTGAAAAAGCTGCATGATGAAAAAATCGAGTCATTGAGAGCTGAATTTCAGTGCTTAGAA CAAAATCACCTGAAGGAATTAGAGGACACACTGCACATCAGGCACACACAGGAGTTTGAGAAAGTTATGA CAGACCACAATATGTCTTTGGAGAAATTAAAAAAAGAAAATCAGCAAAGAATTGACCAGATGCTAGAATC TCATGCCTCAACTATTCAGGAAAAAGAGCAACAGCTGCAGGAGTTGAAACTCAAAGTTTCTGACTTGTCA GACATGAGATGTAAGTTAGAGGTTGAACTTGCACTAAAGGAAGCAGAAACAGATGAGATAAAGATCTTGT TGGAAGAGAGCAGAACACAGCAGAAGGAAATGCTGAAGTCTTTACTTGAACAAGAGACCGAAAACTTAAG AACAGAAATAAGTAAACTAAACCAAAAAATTCATGATAATAATGAGAGTTACCAGGTGGGTTTGTCAGAG TTAAGAGCTTTAATGACAATTGAAAAAGATCAGTGCATTTCAGAGTTAATCAGTAGACATGAAGAAGAAT CTAATATACTTAAGGCTGAATTAGACAATGTTACATCTTTGCATCGCCAAGCATTTGAAATAGAAAAAAA ACTGAAAGAACAAATAGTTGAATTGCAGACTAGATTGAACTCAGAATTGAGTGCTCTTGAAAAACAGAAA GATGAAAAAATAACCCAACAAGAAGAGAAGTATGAAGCACGTATCCAGAACCTTGAGAAAGACAAGGAGA GACTGGTCAAGAACCACGAGCAAGACAAAGAACACTTAATTCAGGAGCTTAATTTTGAAAAAAACAAAGC TGTTCAAACTGCACTAGATGAATTTAAGGTGGAGAGAGAACTTGTTGAGAAAGAGTTATTAGAAAAAGTT AAACATCTTGAGAATCAAATAGCCAAAACTCCTGCCTTTGAGTCAGCCAGAGAAGATTCTTCAAGCTTAG TTGCGGAACTTCAAGAGAAACTTCAAGAAGAAAAAGCTAAGTTTCTGGAACAACTTGAAGAACAAGAGAA AAGAAAGAATGAGGAAATGCAAAATGTCAGAACCTCTTTGATTGCTGAGCAGCAGACCAACTTTAACACA GTCTTAACAAGAGAGAAAATGAGGAAAGAAAACATAATAAATGATCTTAGTGATAAGCTAAAAAGTACAA TGCAGCAGCAAGAGCGGGATAAAGATTTGATAGAGTCGCTCTCTGAGGACCGAGCTCGTTTGCTTGAAGA GAAGAAGCAGCTTGAAGAGGAAGTGAGTAAACTCCGCACTAGCAGTTTTCTTTCCTCAGCACCTGTGGCT GCAGCCCCAGAGCTCTATGGTGCGTGTGCACCTGAGCTCCCAGGGGAGCCAGAGAGATCAGTCATGGAGA CGGCAGATGAAGGAAGACTGGATTCCGCAATGGAGACAAGCATGATGTCTGTCCAAGAAAACATGTTATC TGAAGAGAAGCAGAGGATCATGCTCCTAGAACGGACATTGCAGTTGAAAGAAGAAGAAAACAAGCGGTTA AATCAAAGACTGATGTCTCAGAGTTTGTCCTCAGTCTCTTCAAGGCATTCTGAAAAAATAGCCATTAGAG ATTTTCAGGTGGGAGATTTGGTTCTCATCATCCTAGATGAGCGGCACGACAATTATGTATTGTTTACTGT TAGTCCTACTTTATATTTTCTGCACTCAGAGTCTCTTCCTGCCCTGGATCTCAAACCAGGTGAGGGAGCT TCAGGTGCATCTAGAAGACCCTGGGTCCTTGGGAAAGTAATGGAAAAGGAATACTGTCAAGCCAAAAAGG CACAAAACAGATTTAAAGTTCCTTTGGGGACAAAGTTTTACAGAGTGAAAGCTGTGTCATGGAATAAGAA AGTA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR216914 protein sequence Red=Cloning site Green=Tags(s) MKLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAIQHQVLVVNGGECMAADRRVCTYSAGTDTNP IFLFNKEMILCDRAPAIPKATFSTENDMEIKVEESLMMPAVFHTVASRTQLAVEMYDVAKKLCSFCEGLV HDEHLQHQGWAAIMANLEDCSNSYQKLLFKFESIYSDYLQSIEDIKLKLTHLGTAVSVMAKIPLLECLTR HSYRECLGRPDSLNEHEGSEKAEMKRSTELVLSPDMPRTSNTSLVTSFHKSMEHVAPDPTGTERGKELRE SCQSTVQQEEASVDAKDSDLPFFNVSLLDWINVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTI AKLDNQNMKAIKGLEDRLYALDQMIASCSRLVNEQKELAQGFLANQMRAENLKDASVLPDLCLSHANQLM IMLQNHRKLLDIKQKCTTAKQELANNLHVRLKWCCFVMLHADQDGEKLQALLRLVIELLERVRIVEALST VPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESFGKLFRKSFLRNRLFKGLDSWPSS FCTQKPRKFDCELPDISLKDLQFLQSFCPSEVQPFLRVPLLCDFEPLHQHVLALHNLVKAAQSLDEMSQT ITDLLNEQKVSTSQASPQSAASPRIESTTGITTTTSPKTPPPLTVQDTLCPAVCPLEELSPDSIDAHTFD FETISHPNTEQPVHQASIDLDSLAESPESDFMSAVNEFVIEENLSSPNPISDPQSPEMMVESLYSSVINA IDSRRMQDTSTRGNEGFGDRAALHVQLEKCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTA VEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDN EFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLE QNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLS DMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSE LRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAFEIEKKLKEQIVELQTRLNSELSALEKQK DEKITQQEEKYEARIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKV KHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNT VLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLSSAPVA AAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRL NQRLMSQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGEGA SGASRRPWVLGKVMEKEYCQAKKAQNRFKVPLGTKFYRVKAVSWNKKV TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
| ACCN | NM_009826 |
| ORF Size | 4767 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_009826.1, NM_009826.2, NM_009826.3, NM_009826.4, NP_033956.2 |
| RefSeq Size | 7046 bp |
| RefSeq ORF | 4767 bp |
| Locus ID | 12421 |
| UniProt ID | Q9ESK9 |
| Cytogenetics | 1 A1 |
| MW | 182.4 kDa |
| Gene Summary | Involved in autophagy (PubMed:23262492, PubMed:19258318). Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1 (PubMed:23392225, PubMed:23285000, PubMed:19258318). Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy (PubMed:21525242). Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis (PubMed:21807966). Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways (By similarity). Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111 (PubMed:21795712). Functions as a DNA-binding transcription factor (PubMed:12095676). Is a potent regulator of the RB1 pathway through induction of RB1 expression (PubMed:15968549). Plays a crucial role in muscular differentiation (PubMed:15968549). Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis (PubMed:19940130, PubMed:21088496).[UniProtKB/Swiss-Prot Function] |
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Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| MC224720 | Rb1cc1 (untagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1), (10ug) | 1 359,00 EUR | |
| MG216914 | Rb1cc1 (tGFP-tagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1), (10ug) | 1 559,00 EUR | |
| MR216914L3 | Lenti ORF clone of Rb1cc1 (Myc-DDK-tagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1) | 1 659,00 EUR | |
| MR216914L4 | Lenti ORF clone of Rb1cc1 (mGFP-tagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1) | 1 659,00 EUR |