This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants.
Positive regulation of transcription, DNA-dependent
681
Regulation of transcription, DNA-dependent
1734
Transcription initiation from RNA polymerase II promoter
69
Cellular components
Name
# of Products
Nucleoplasm
775
Nucleus
4914
Transcription factor complex
286
Protein function
Name
# of Products
Core promoter binding
51
Cyclin-dependent protein kinase activity
102
DNA binding
3958
Protein binding
12191
Sequence-specific DNA binding transcription factor activity
2776
What is the species homology for "E2F3 Antibody - middle region (ARP76104_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".
How long will it take to receive "E2F3 Antibody - middle region (ARP76104_P050)"?
This item is available "Domestic: within 24 hours delivery | International: 3-5 days".
What buffer format is "E2F3 Antibody - middle region (ARP76104_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.". Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "E2F3 Antibody - middle region (ARP76104_P050)"?
This target may also be called "E2F-3" in publications.
What is the shipping cost for "E2F3 Antibody - middle region (ARP76104_P050)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
What is the guarantee for "E2F3 Antibody - middle region (ARP76104_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "E2F3 Antibody - middle region (ARP76104_P050)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "49 kDa". Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "E2F3 Antibody - middle region (ARP76104_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "E2F3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "E2F3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "E2F3"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "E2F3"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "E2F3"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "E2F3"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
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