Biotrend > PXN Antibody
PXN Antibody
Brand : Aviva Systems Biology
Request more information
Please log in to use this feature.
Size:100 uL
Bulk
Order
Order
Aviva's
Satisfaction
Guarantee
Satisfaction
Guarantee
Contact Us:
- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
Shipping Info:
- : Antibody & Protein in US
- + /Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for anti-PXN (OASG05701) antibody |
---|
Predicted Species Reactivity | Human, Mouse, Rat, Monkey |
---|---|
Product Format | Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | WB, IHC, IF |
Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
Immunogen | Synthesized peptide derived from human Paxillin around the non-phosphorylation site of Y31. Location: 10-90aa. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration | 1 mg/ml |
Specificity | Paxillin Polyclonal Antibody detects endogenous levels of Paxillin protein. |
Application Info | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; |
Gene Symbol | PXN |
---|---|
Gene Full Name | paxillin |
Alias Symbols | PXN, Paxillin |
NCBI Gene Id | 5829; 19303; 360820 |
Description of Target | This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). |
Uniprot ID | P49023, Q8VI36, Q66H76 |
Molecular Weight | 68 kDa |
Protein interactions
Name | # of Products |
---|---|
AR | 434 |
ARHGEF7 | 55 |
ASAP1 | 27 |
ASAP2 | 17 |
BCAR1 | 121 |
CASP3 | 324 |
CBL | 471 |
CRKL | 155 |
EPHB1 | 18 |
GIT1 | 87 |
GIT2 | 24 |
GSK3A | 63 |
GSK3B | 566 |
ILK | 145 |
ITGA9 | 19 |
LIMK1 | 27 |
MAPK3 | 444 |
MAPK8 | 256 |
MATK | 35 |
NCK1 | 212 |
NEDD9 | 103 |
NF2 | 66 |
PABPC1 | 119 |
PAK1 | 162 |
PARVA | 40 |
PDPK1 | 188 |
PKD1 | 63 |
PPP2CA | 290 |
PPP2R5C | 18 |
PTEN | 158 |
PTK2 | 335 |
PTK2B | 182 |
PTPN12 | 65 |
PTPRH | 13 |
PXN | 226 |
REPS2 | 15 |
RNF5 | 25 |
SDC4 | 52 |
SORBS1 | 53 |
SYK | 252 |
TRIP6 | 94 |
TUBA1B | 43 |
TUBA3C | 23 |
TUBA8 | 13 |
TUBG2 | 6 |
Biological pathways
Name | # of Products |
---|---|
Cell junction assembly | 146 |
Cell-matrix adhesion | 263 |
Cellular response to reactive oxygen species | 11 |
Epidermal growth factor receptor signaling pathway | 240 |
Growth hormone receptor signaling pathway | 33 |
Muscle contraction | 120 |
Signal complex assembly | 40 |
Biological process
Name | # of Products |
---|---|
Activation of MAPK activity | 105 |
Branching morphogenesis of a tube | 37 |
Cell adhesion | 446 |
Cell junction assembly | 63 |
Cellular component movement | 86 |
Cellular response to reactive oxygen species | 10 |
Cytoskeleton organization | 97 |
Epidermal growth factor receptor signaling pathway | 124 |
Focal adhesion assembly | 17 |
Growth hormone receptor signaling pathway | 14 |
Lamellipodium assembly | 19 |
Muscle contraction | 66 |
Peptidyl-tyrosine phosphorylation | 72 |
Signal complex assembly | 8 |
Signal transduction | 1058 |
Cellular components
Name | # of Products |
---|---|
Cell cortex | 99 |
Cell junction | 414 |
Cytoplasm | 4549 |
Cytoskeleton | 630 |
Focal adhesion | 101 |
Lamellipodium | 74 |
Microtubule associated complex | 23 |
Plasma membrane | 2678 |
Protein function
Name | # of Products |
---|---|
Beta-catenin binding | 138 |
BH4 domain binding | 3 |
Metal ion binding | 5514 |
Protein binding | 12191 |
Vinculin binding | 26 |
Zinc ion binding | 3721 |
- PXN Antibody (OABB00755)Catalog #: OABB00755Clone: PolyclonalSpecies Tested: Human, RatApplication: FC, ICC, IHC-Fr, IHC-P, IPFormat: Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.Size: 100UG
- Paxillin Antibody (Phospho-Tyr118) (OAEC00088)Catalog #: OAEC00088Application: WB, IHCFormat: LiquidSize: 50ug
- PXN Antibody - N-terminal region (ARP30405_T100)Catalog #: ARP30405_T100Species Tested: HumanApplication: WBFormat: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- PXN Antibody - N-terminal region (ARP72626_P050)Catalog #: ARP72626_P050Species Tested: HumanApplication: WBFormat: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.