Ponceau 4R [2611-82-7]
Cat# HY-D0193-1g
Size : 1g
Brand : MedChemExpress
Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids.
For research use only. We do not sell to patients.
Ponceau 4R Chemical Structure
CAS No. : 2611-82-7
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This product is a controlled substance and not for sale in your territory.
- •Small. 2023 Aug 21;e2207606. [Abstract]
Biological Activity
Purity & Documentation
References
Customer Review
Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids. | ||||||||||||||||
In Vivo | Ponceau 4R (31, 37, 137 mg/kg for cats, dogs, fish, added to feed) is a maximum safe dose with no effect on cats, dogs and fish. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||||||||
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604.47 | ||||||||||||||||
C20H11N2Na3O10S3 | ||||||||||||||||
2611-82-7 | ||||||||||||||||
Solid | ||||||||||||||||
Brown to red | ||||||||||||||||
O=S(C1=C2C(/N=N/C3=C4C=CC=CC4=C(S(=O)(O[Na])=O)C=C3)=C(O)C=CC2=CC(S(=O)(O[Na])=O)=C1)(O[Na])=O | ||||||||||||||||
Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) | ||||||||||||||||
In Vitro: H2O : 25 mg/mL (41.36 mM; Need ultrasonic) DMSO : 10 mg/mL (16.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing Stock Solutions
View the Complete Stock Solution Preparation Table * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo: Select the appropriate dissolution method based on your experimental animal and administration route. For the following dissolution methods, please ensure to first prepare a clear stock solution using an and then sequentially add co-solvents:
For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details. The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE). | ||||||||||||||||
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[1]. Rychen G, et al. Safety and efficacy of ponceau 4R for cats, dogs and ornamental fish. EFSA J. 2018 Mar 29;16(3):e05222.
[2]. Dong Y, et al. Quantification of Ponceau 4R in Foods by Indirect Competitive Enzyme-Linked Immunosorbent Assay (icELISA). J Agric Food Chem. 2015 Jul 22;63(28):6338-45.
* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO / H2O | 1 mM | 1.6543 mL | 8.2717 mL | 16.5434 mL | 41.3585 mL |
5 mM | 0.3309 mL | 1.6543 mL | 3.3087 mL | 8.2717 mL | |
10 mM | 0.1654 mL | 0.8272 mL | 1.6543 mL | 4.1359 mL | |
15 mM | 0.1103 mL | 0.5514 mL | 1.1029 mL | 2.7572 mL | |
H2O | 20 mM | 0.0827 mL | 0.4136 mL | 0.8272 mL | 2.0679 mL |
25 mM | 0.0662 mL | 0.3309 mL | 0.6617 mL | 1.6543 mL | |
30 mM | 0.0551 mL | 0.2757 mL | 0.5514 mL | 1.3786 mL | |
40 mM | 0.0414 mL | 0.2068 mL | 0.4136 mL | 1.0340 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Ponceau 4R2611-82-7Acid Red 18 New CoccineAcid Red18Acid Red-18Fluorescent Dyecats and dogscolourantornamental fishsafetyInhibitorinhibitorinhibit
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