Specifications

Product Data
Applications	IHC
Recommended Dilution	IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivities	Human, Mouse
Host	Rabbit
Isotype	IgG
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 555-847 amino acids of human piwi-like RNA-mediated gene silencing 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Gene Name	piwi like RNA-mediated gene silencing 1
Database Link	NP_004755 Entrez Gene 57749 MouseEntrez Gene 9271 Human UniProt ID Q96J94
Background	This gene encodes a member of the PIWI subfamily of Argonaute proteins; evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal; RNA silencing; and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	CT80.1; HIWI; MIWI; PIWI
Reference Data
Protein Pathways	Dorso-ventral axis formation