Phosal 50 PG is a cosolvent (standardised phosphatidylcholine concentrate). Phosal 50 PG as a carrier for lipophilic compounds, can improve the absorption, efficacy and therapeutic index of the active ingredient^[1].

Phosal 50 PG is usually used as a cosolvent.
Navitoclax (HY-10087) (100 mg/kg, once a day for 21 days) is formulated in 10% ethanol, 30% polyethylene glycol 400, and 60% Phosal 50 PG and administered p.o. to mice^[2].
A-1331852 (HY-19741) (25 mg/kg, daily for 10 days) is formulated in 2.5% DMSO, 10% ethanol, 27.5% PEG 300, and 60% Phosal 50 PG and administered p.o. to mice^[3].
Venetoclax (HY-15531) (100 mg/kg, daily for 10 days) is formulated in 10% ethanol, 30% PEG 400, 60% Phosal 50 PG and administered p.o. to mice^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

774594-96-6

Liquid

Light yellow to yellow

[Phosal 50 PG]

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

• [1]. Khani S, et al. Improved oral bioavalability of mebudipine upon administration in PhytoSolve and Phosal-based formulation (PBF). AAPS PharmSciTech. 2014 Feb;15(1):96-102.  [Content Brief]