General Info
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 34pg/mL |
| Detection Limit: | 78.1-5000pg/mL |
| Short Description: | This TRPM7 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
Information
| Gene Symbol: | Trpm7 |
| Gene ID: | 58800 |
| Uniprot ID: | TRPM7_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
Description
| Tissue Specificity | Found to be expressed in brain and skeletal muscle, with stronger signals in kidney, heart, liver and spleen. |
| Post Translational Modifications | Autophosphorylated. |
| Function | Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). |
| Protein Name | Transient Receptor Potential Cation Channel Subfamily M Member 7Channel-Kinase 1Long Transient Receptor Potential Channel 7Ltrpc-7Ltrpc7Transient Receptor Potential-Phospholipase C-Interacting KinaseTrp-Plik |
| Database Links | Reactome: R-MMU-3295583 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Transient Receptor Potential Cation Channel Subfamily M Member 7 ELISA kitChannel-Kinase 1 ELISA kitLong Transient Receptor Potential Channel 7 ELISA kitLtrpc-7 ELISA kitLtrpc7 ELISA kitTransient Receptor Potential-Phospholipase C-Interacting Kinase ELISA kitTrp-Plik ELISA kitTrpm7 ELISA kitChak ELISA kitLtrpc7 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance