General Info
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.042ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This NCL Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Information
Gene Symbol: | Ncl |
Gene ID: | 17975 |
Uniprot ID: | NUCL_MOUSE |
Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Description
Tissue Specificity | Expressed in B-cells that have been induced to switch to various Ig isotypes. |
Post Translational Modifications | Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group. Symmetrically methylated by PRMT5. |
Function | Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. |
Protein Name | NucleolinProtein C23 |
Database Links | Reactome: R-MMU-6791226 |
Cellular Localisation | NucleusNucleolusCytoplasmLocalized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas |
Alternative ELISA Names | Nucleolin ELISA kitProtein C23 ELISA kitNcl ELISA kitNuc ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance