Mouse Hdac6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hdac6
Locus ID	15185
Kit Components	GA201864G1, Hdac6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201864G2, Hdac6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201864G3, Hdac6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001130416, NM_010413
UniProt ID	Q9Z2V5
Synonyms	Hd6; Hdac5; mHDA2; Sfc6
Summary	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.[UniProtKB/Swiss-Prot Function]