Mouse ErbB3 (V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3) Sandwich ELISA Kit E0008690)

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Erbb3
Gene ID:	13867
Uniprot ID:	ERBB3_MOUSE
Sample Type:	serum, plasma or other biological fluids.

Tissue Specificity	In the muscle, expression localizes to the synaptic sites of muscle fibers.
Post Translational Modifications	Autophosphorylated. Ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase.
Function	Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it.ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.
Protein Name	Receptor Tyrosine-Protein Kinase Erbb-3 Glial Growth Factor Receptor Proto-Oncogene-Like Protein C-Erbb-3
Database Links	Reactome: R-MMU-1227986 Reactome: -MMU-1236394 Reactome: -MMU-1250196 Reactome: -MMU-1257604 Reactome: -MMU-1306955 Reactome: -MMU-1358803 Reactome: -MMU-1963642 Reactome: -MMU-5673001 Reactome: -MMU-6785631 Reactome: -MMU-6811558 Reactome: -MMU-8847993 Reactome: -MMU-8863795
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative ELISA Names	Receptor Tyrosine-Protein Kinase Erbb-3 ELISA kit Glial Growth Factor Receptor ELISA kit Proto-Oncogene-Like Protein C-Erbb-3 ELISA kit Erbb3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance