MMP10 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommended Dilution	WB: 500-2000 WB positive control: NIH/3T3 cells IHC: 15-50 Positive control: Human lung cancer Predicted cell location: Cytoplasm
Reactivities	Human, Mouse
Host	Rabbit
Isotype	IgG
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 404-418 amino acids of human matrix metallopeptidase 10 (stromelysin 2)
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Predicted Protein Size	54 kDa
Gene Name	matrix metallopeptidase 10
Database Link	NP_002416 Entrez Gene 17384 MouseEntrez Gene 4319 Human UniProt ID P09238
Background	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; and tissue remodeling; as well as in disease processes; such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Synonyms	SL-2; STMY2
Note	Antibody has been shown to cross react with MMP3 protein.
Reference Data
Protein Families	Druggable Genome, Protease