MLH1 Mouse Monoclonal Antibody [Clone ID: OTI3C1]
CAT#: TA810261
MLH1 mouse monoclonal antibody,clone OTI3C1
Size: 30 ul
Formulation: Carrier-Free
Conjugation: Biotin HRP
Specifications
| Product Data | |
| Clone Name | OTI3C1 |
| Applications | IHC, WB |
| Recommended Dilution | WB 1:500~2000, IHC 1:1000 |
| Reactivities | Human, Mouse, Rat |
| Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 299-527 of human MLH1(NP_000240) produced in E.coli. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 84.4 kDa |
| Gene Name | mutL homolog 1 |
| Database Link | |
| Background | This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009] |
| Synonyms | COCA2; FCC2; hMLH1; HNPCC; HNPCC2; MMRCS1 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Colorectal cancer, Endometrial cancer, Mismatch repair, Pathways in cancer |
Documents
| Product Manuals |
| FAQs |
|
| SDS |
Resources
| Antibody Resources |
|
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| CF810261 | Carrier-free (BSA/glycerol-free) MLH1 mouse monoclonal antibody,clone OTI3C1 | 600,00 EUR | |
| TA810261AM | MLH1 mouse monoclonal antibody,clone OTI3C1, Biotinylated | 509,00 EUR | |
| TA810261BM | MLH1 mouse monoclonal antibody,clone OTI3C1, HRP conjugated | 509,00 EUR | |
| TA810261S | MLH1 mouse monoclonal antibody,clone OTI3C1 | 200,00 EUR |