MHC Class II (RT1B) Antibody - PE Conjugated
Cat# OASA04223
Size : 100Tests
Brand : Aviva Systems Biology
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MHC Class II (RT1B) Antibody - PE Conjugated (OASA04223)
| Datasheets/Manuals | Printable datasheet for MHC Class II (RT1B) Antibody - PE Conjugated (OASA04223) |
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| Predicted Species Reactivity | Rat |
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| Product Format | Lyophilized. Phosphate buffered saline |
| Clonality | Monoclonal |
| Clone | OX-6 |
| Isotype | IgG1 |
| Host | Mouse |
| Conjugation | R-PE |
| Application | FC |
| Additional Information | Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the NS1 mouse myeloma cell line. |
| :: | Preparation: Purified IgG prepared by affinity chromatography on Protein G Preservative Stabilisers: 0.09% - Sodium Azide 1% - Bovine Serum Albumin |
| :: | Buffer Solutions: Phosphate buffered saline pH7.2 |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Rat thymocyte membrane glycoproteins. |
| Purification | Protein A Purified |
| Predicted Homology Based on Immunogen Sequence | Rat |
| Specificity | MHC CLASS II RT1B |
| Application Info | Flow Cytometry: Neat - 1/10 |
| Application Data | Application #1: Rat Spleen Tissue lysate probed with Mouse anti Rat MHC Class II RT1B Application #2: Staining of rat spleen cells with Mouse anti Rat RT1B  Application #3: Staining of rat spleen cells with Mouse anti Rat RT1B: Alexa Fluor 488  Application #4: Staining of rat spleen cells with Mouse anti Rat RT1B: FITC  Application #5: Staining of rat spleen cells with Mouse anti Rat RT1B: FITC  |
| Reference | 1. McMaster, W. R. and Williams, A. F. (1979) Identification of Ia glycoproteins in rat thymus and purification from rat spleen Eur. J. Immunol. 9: 426-433. 2. Fernandez, J. L. and Weeks, M. (1986) Genetic monitoring of inbred strains of mice using monoclonal antibodies to major histocompatibility haplotypes and lymphocyte alloantigens. Lab. Anim. 20: 293-297. 3. Charteris, D. G. and Lightman, S. L. (1993) In vivo lymphokine production in experimental autoimmune uveoretinitis. Immunology. 78: 387-392. 4. Whiteland, J. L. et al. (1995) Immunohistochemical detection of T-cell subsets and other leucocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies. J. Histochem. Cytochem. 43: 313-320. 5. McKechnie, N. M. et al. (1997) Immunization with the cross-reactive antigens Ov39 from Onchocerca volvulus and hr44 from human retinal tissue induces ocular pathology and activates retinal microglia. J. Infect. Dis. 176: 1334-1343. 6. Male, D. K. et al. (1987) Serological evidence for a defect in RT1.B (I-A) expression by the BDIX rat strain J. Immunogenet. 14: 301-312. 7. Burrows, G. G. et al. (1998) Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis. J. Immunol. 161: 5987-5996. 8. Zilka, N. et al. (2009) Human misfolded truncated tau protein promotes activation of microglia and |
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| Protein Name | Rano class II histocompatibility antigen, A beta chain |
| Description of Target | MOUSE ANTI RAT MHC CLASS II RT1B:RPE |
| Uniprot ID | P06341 |
