Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-SelenoMethionine [3211-76-5]
Cat# T5372-50mg
Size : 50mg
Brand : TargetMol
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L-SelenoMethionine
Catalog No. T5372 CAS 3211-76-5
Synonyms: L-(+)-Selenomethionine
L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase.
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L-SelenoMethionine, CAS 3211-76-5
| Description | L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase. |
| In vitro | At 5 μM, L-selenomethionine selectively induces apoptosis in LNCaP prostate cancer cells without affecting non-cancerous cells [1]. c-Myc, cyclin C, proliferating cell nuclear antigen, cyclin-dependent kinase (cdk)1, cdk2, cdk4, cyclin B and cyclin D2 mRNA levels were lower in selenium-deficient cells than in the cells supplemented with 0.25 micromol/L selenomethionine. The phosphorylation state of total cellular protein was higher (57%) in selenium-supplemented cells than in selenium-deficient cells [2]. |
| Synonyms | L-(+)-Selenomethionine |
| Molecular Weight | 196.11 |
| Formula | C5H11NO2Se |
| CAS No. | 3211-76-5 |
Storage
Solubility Information
DMSO: 2.5 mM, Sonication is recommended.
H2O: 30 mg/mL(152.97 mM), Sonication is recommended.
References and Literature
1. Stewart J, et al. Effects of selenomethionine on the gene expression profile of cloned human prostate cancer cells representing a phenotypic continuum of cancer progression. Nutr Cancer. 2008;60(6):826-36. 2. Zeng H. Selenite and selenomethionine promote HL-60 cell cycle progression. J Nutr. 2002 Apr;132(4):674-9.