General Info
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 31.25 pg/mL |
| Detection Limit: | 625-4000 pg/mL |
| Short Description: | This IFNL1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Conjugation: | Biotin |
| Storage Instruction: | Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month. |
| Assay Time: | 4 hours |
| Detection: | Colorimetric |
Information
| Gene Symbol: | IFNL1 |
| Gene ID: | 282618 |
| Uniprot ID: | IFNL1_HUMAN |
| Sample Type: | serum, plasma and cell culture supernates |
Description
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. |
| Protein Name | Interferon Lambda-1Ifn-Lambda-1Cytokine Zcyto21Interleukin-29Il-29 |
| Database Links | Reactome: R-HSA-449836Reactome: R-HSA-8854691 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Interferon Lambda-1 ELISA kitIfn-Lambda-1 ELISA kitCytokine Zcyto21 ELISA kitInterleukin-29 ELISA kitIl-29 ELISA kitIFNL1 ELISA kitIL29 ELISA kitZCYTO21 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance