Human Glycogenin 1 (GYG1) activation kit by CRISPRa

CAT#: GA102030

GYG1 CRISPRa kit - CRISPR gene activation of human glycogenin 1



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol GYG1
Locus ID 2992
Kit Components

GA102030G1, Glycogenin 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102030G2, Glycogenin 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102030G3, Glycogenin 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001184720, NM_001184721, NM_004130
UniProt ID P46976
Synonyms GSD15; GYG
Summary This gene encodes a member of the glycogenin family. Glycogenin is a glycosyltransferase that catalyzes the formation of a short glucose polymer from uridine diphosphate glucose in an autoglucosylation reaction. This reaction is followed by elongation and branching of the polymer, catalyzed by glycogen synthase and branching enzyme, to form glycogen. This gene is expressed in muscle and other tissues. Mutations in this gene result in glycogen storage disease XV. This gene has pseudogenes on chromosomes 1, 8 and 13 respectively. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]

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