Human COPR5 (Cooperator Of PRMT5) Sandwich ELISA Kit Ready-To-Use

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	COPRS
Gene ID:	55352
Uniprot ID:	COPRS_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression. Plays a role in muscle cell differentiation by modulating the recruitment of PRMT5 to the promoter of genes involved in the coordination between cell cycle exit and muscle differentiation.
Protein Name	Coordinator Of Prmt5 And Differentiation Stimulator Cooperator Of Prmt5 Protein Ttp1
Database Links	Reactome: R-HSA-3214858
Cellular Localisation	Nucleus
Alternative ELISA Names	Coordinator Of Prmt5 And Differentiation Stimulator ELISA kit Cooperator Of Prmt5 ELISA kit Protein Ttp1 ELISA kit COPRS ELISA kit C17orf79 ELISA kit COPR5 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance