Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glycochenodeoxycholic Acid [640-79-9]
Cat# T4588-25mg
Size : 25mg
Brand : TargetMol
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Glycochenodeoxycholic Acid
Catalog No. T4588 CAS 640-79-9
Synonyms: Glycine chenodeoxycholate, Chenodeoxycholylglycine, GCDCA, Glycochenodeoxycholate, Lithocholylglycine
Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children.
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Glycochenodeoxycholic Acid, CAS 640-79-9
| Description | Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children. |
| Synonyms | Glycine chenodeoxycholate, Chenodeoxycholylglycine, GCDCA, Glycochenodeoxycholate, Lithocholylglycine |
| Molecular Weight | 449.62 |
| Formula | C26H43NO5 |
| CAS No. | 640-79-9 |
Storage
Solubility Information
H2O: Insoluble
DMSO: 82 mg/mL(182.4 mM)
References and Literature
1. Kuipers F, Derksen JP, Gerding A, Scherphof GL, Vonk RJ. Biliary lipid secretion in the rat. The uncoupling of biliary cholesterol and phospholipid secretion from bile acid secretion by sulfated glycolithocholic acid. Biochim Biophys Acta. 1987 Nov 21;922(2):136-44. 2. Kuipers F, Hardonk MJ, Vonk RJ, van der Meer R. Bile secretion of sulfated glycolithocholic acid is required for its cholestatic action in rats. Am J Physiol. 1992 Feb;262(2 Pt 1):G267-73.