Flurbiprofen-d5 [215175-76-1]
Cat# HY-10582S1-1mg
Size : 1mg
Brand : MedChemExpress
Flurbiprofen-d5 is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3].
For research use only. We do not sell to patients.
Flurbiprofen-d5 Chemical Structure
CAS No. : 215175-76-1
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of Flurbiprofen-d5:
- Flurbiprofen In-stock
Description |
Flurbiprofen-d5 is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3]. |
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In Vitro |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Molecular Weight |
249.29 |
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Formula |
C15H8D5FO2 |
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CAS No. |
215175-76-1 |
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Unlabeled CAS |
5104-49-4 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
FC1=C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C=CC(C(C)C(O)=O)=C1 |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
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Solvent & Solubility |
In Vitro:
DMSO : ≥ 100 mg/mL (401.14 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) *"≥" means soluble, but saturation unknown. Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
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Purity & Documentation |
Purity: ≥99.0% |
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References |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO | 1 mM | 4.0114 mL | 20.0570 mL | 40.1139 mL | 100.2848 mL |
5 mM | 0.8023 mL | 4.0114 mL | 8.0228 mL | 20.0570 mL | |
10 mM | 0.4011 mL | 2.0057 mL | 4.0114 mL | 10.0285 mL | |
15 mM | 0.2674 mL | 1.3371 mL | 2.6743 mL | 6.6857 mL | |
20 mM | 0.2006 mL | 1.0028 mL | 2.0057 mL | 5.0142 mL | |
25 mM | 0.1605 mL | 0.8023 mL | 1.6046 mL | 4.0114 mL | |
30 mM | 0.1337 mL | 0.6686 mL | 1.3371 mL | 3.3428 mL | |
40 mM | 0.1003 mL | 0.5014 mL | 1.0028 mL | 2.5071 mL | |
50 mM | 0.0802 mL | 0.4011 mL | 0.8023 mL | 2.0057 mL | |
60 mM | 0.0669 mL | 0.3343 mL | 0.6686 mL | 1.6714 mL | |
80 mM | 0.0501 mL | 0.2507 mL | 0.5014 mL | 1.2536 mL | |
100 mM | 0.0401 mL | 0.2006 mL | 0.4011 mL | 1.0028 mL |
Flurbiprofen-d5 Related Classifications
- Immunology/Inflammation Apoptosis
- COX Apoptosis
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Flurbiprofen-d5215175-76-1dl-Flurbiprofen-d5COXApoptosisCyclooxygenaseInhibitorinhibitorinhibit