Description
CXCR4 antagonist (IC50 = 126 nM). Displays anti-HIV activity in assays using NL4-3 and IIIB strains (EC50 = 21 nM for both strains).
Size : 1mg
White lyophilised solid.
606968-52-9
VD-OEIA-1025
C36H47N11O6
729.84
>=99%
Soluble to 2 mg/ml in 20% acetonitrile/H2O
-20°C.
XGYRR (Modifications: Cyclic peptide, X = 2-Nal, Tyr-3 = D-Tyr]
10mg, 1mg
CXCR4 antagonist (IC50 = 126 nM). Displays anti-HIV activity in assays using NL4-3 and IIIB strains (EC50 = 21 nM for both strains).
1.Tamamura et al (2005).J.Med.Chem. 48 380.
2.Inokuchi et al (2011). ACS Med.Chem.Lett. 2 477.