ENaC Gamma Antibody
Cat# OASE00462
Size : 100ug
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
ENaC Gamma Antibody (OASE00462)
| Datasheets/Manuals | Printable datasheet for ENaC Gamma Antibody (OASE00462) |
|---|---|
| COA Datasheet | 1 µg/ml of SPC-405 was sufficient for detection of gamma-ENaC in 20 µg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody. |
| Predicted Species Reactivity | Hamster|Human|Mouse|Rat|Xenopus|Xenopus laevis |
|---|---|
| Product Format | Liquid. PBS with 50% glycerol and 0.09% sodium azide. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | ICC,IF,IHC,WB |
| :: | Certificate of Analysis: 1 ug/mL was sufficient for detection of gamma-ENaC in 20ug of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody. |
| Reconstitution and Storage | -20°C |
| Immunogen | Produced against the C-terminal tail (amino acids 629-650) of rat gamma ENaC (antibody designation L550) |
| Purification | Protein A Purified |
| Concentration | 1 mg/ml |
| Specificity | Detects ~83kDa. |
| Dilution | WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user. |
| Storage Buffer | PBS, 50% glycerol, 0.09% sodium azide |
| Reference | 1. Kakizoe Y., et al. (2009) J Hpyertens. 27(8): 1679-1689. 2. Gu Y. (2008) J Cell Physiol. 216(2):453-457. 3. Bruns J.B. (2003) Am J Physiol Renal Physiol. 285(4): F600-F609. 4. Mauro T., et al. (2002) J Invest Dermatol. 118(4): 589-594. 5. Elias N., et al. (2007) Am J Physiol Lung Cell Mol Physiol. 293(3): L537-45. 6. Dyka F.M., May C.A. and Enz R. (2005) J Neurochem. 94(1): 120-128. |
|---|---|
| Gene Symbol | Scnn1g |
| Gene Full Name | sodium channel epithelial 1 subunit gamma |
| Alias Symbols | amiloride sensitive sodium channel gamma1 subunit, amiloride-sensitive sodium channel subunit gamma, ENaC, epithelial Na(+) channel subunit gamma, epithelial sodium channel gamma subunit, gamma-ENaC, gamma-NaCH, nonvoltage-gated sodium channel 1 subunit gamma, SCNEG, sodium channel epithelial 1 gamma subunit, sodium channel, non-voltage-gated 1, gamma subunit, Sodium channel, nonvoltage-gated 1, gamma (epithelial), sodium channel, nonvoltage-gated, type I, gamma. |
| NCBI Gene Id | 24768 |
| Protein Name | Amiloride-sensitive sodium channel subunit gamma|amiloride-sensitive sodium channel subunit gamma [Rattus norvegicus] |
| Description of Target | Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. |
| Uniprot ID | P37091 |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_058742 |
