Ciprofloxacin Hydrochloride 10mg/ml
Cat# C5075-5x10ml
Size : 5x10ml
Brand : US Biological
Contact local distributor :
Phone : +1 850 650 7790
Grade
Molecular Biology GradeShipping Temp
Blue IceStorage Temp
-20°CSterile-filtered aqueous solution
Ciprofloxacin Hydrochloride is a high activity fluoroquinolone antibiotic effective against a broad spectrum of gram positive and negative bacteria such as Pseudomonas, Salmonella, streptococcus and Staphylococcus. Effective against mycoplasma (12 days). Ciprofloxacin differs from other quinolones in that it has a fluorine atom at the 6-position, a piperazine moiety at the 7-position, and a cyclopropyl ring at the 1-position. The bactericidal action of ciprofloxacin results from interference with the enzyme DNA gyrase which is needed for the synthesis of bacterial DNA. Ciprofloxacin has been shown to be active against most strains of the following organisms:
Gram-Positive Bacteria:
Enterococcus faecalis (Many strains are only moderately susceptible); Staphylococcus haemolyticus; Staphylococcus hominis; Staphylococcus saprophyticus; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae; Streptococcus pyogenes.
Gram-Negative Bacteria:
Acinetobacter calcoaceticus subs. anitratus; Acinetobacter calcoaceticus subs. Iwoffi; Aeromonas caviae; Aeromonas hydrophila; Brucella melitensis; Campylobacter coli; Campylobacter jejuni; Citrobacter diversus; Citrobacter freundii; Edwardsiella tarda; Enterobacter aerogenes; Enterobacter cloacae; Escherichia coli; Haemophilus ducreyi; Haemophilus influenzae; Haemophilus parainfluenzae; Klebsiella oxytoca; Klebsiella pneumoniae; Legionella pneumophila; Moraxella (Branhamella) catarrhalis; Morganella morganii; Neisseria gonorrhoeae; Neisseria meningitidis; Pasteurella multocida; Proteus mirabilis; Proteus vulgaris; Providencia rettgeri; Providencia stuartii; Pseudomonas aeruginosa; Salmonella enteritidis; Salmonella typhi; Serratia marcescens; Shigella flexneri; Shigella sonnei; Vibrio cholerae; Vibrio parahaemolyticus; Vibrio vulnificus; Yersinia enterocolitica.
Other Organisms:
Chlamydia trachomatis (only moderately susceptible); Mycobacterium tuberculosis (only moderately susceptible).
Other Organisms:
Chlamydia trachomatis (only moderately susceptible); Mycobacterium tuberculosis (only moderately susceptible).
Also Available:
C5074: Ciprofloxacin Hydrochloride
Synonyms:
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid Hydrochloride; Bay Q3939 Hydrochloride
CAS No:
86393-32-0
Molecular Formula:
C17H18FN3O3•HCl
Molecular Weight:
385.8
Purity:
98-102%
Appearance (powder):
Faintly yellowish to light yellow crystalline powder
pH:
3.0-4.5 (The pH for 0.2% infusion solutions is 3.5-4.6).
Heavy Metals:
≤0.002%
Loss on Drying:
4.7-6.7%
Fluoroquinolonic Acid:
≤0.2%
Solubility:
Water: 3.5g/dL
Methanol: 0.21g/dL
Acetic acid: 0.14g/dL
Ethanol: 0.016g/dL
Water and 0.1M NaOH: Solutions are stable to hydrolysis for 16 hrs. at 90°C.
0.1M HCl: Displays slight decarboxylation.
Turbidity can be cleared by heat to 30-50°C
Methanol: 0.21g/dL
Acetic acid: 0.14g/dL
Ethanol: 0.016g/dL
Water and 0.1M NaOH: Solutions are stable to hydrolysis for 16 hrs. at 90°C.
0.1M HCl: Displays slight decarboxylation.
Turbidity can be cleared by heat to 30-50°C
Working Concentration:
Effective at low concentrations (10ug/ml) in water and buffered media.
Concentration:
10mg/ml
Form:
Supplied as a liquid in dH2O, sterile-filtered.
Appearance:
Pale yellow to light yellow, clear, complete. Turbidity after thawing can be cleared by heat to 30-50°
Working Concentration:
Effective at low concentrations (10ug/ml) in water and buffered media.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note:
Solutions should be protected from light. In water, solutions are stable to hydrolysis for 16 hrs. at 90°C..
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
All products should be handled by qualified personnel only, trained in laboratory procedures.