Chd7 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN303251LP
Chd7 - mouse gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro RFP-BSD mBFP-Neo
HDR-mediated knockout kit validation
Product Images
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
| Donor DNA | Luciferase-Puro |
| Symbol | Chd7 |
| Locus ID | 320790 |
| Components | KN303251G1, Chd7 gRNA vector 1 in pCas-Guide CRISPR vector KN303251G2, Chd7 gRNA vector 2 in pCas-Guide CRISPR vector KN303251LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001081417, NM_001277149, NM_001033395 |
| UniProt ID | A2AJK6 |
| Synonyms | A730019I05Rik; Cycn; Cyn; Dz; Edy; Flo; Lda; Mt; Obt; RP23-464N23.1; Todo; WBE1; Whi |
| Summary | This gene encodes a protein containing two chromodomains and an ATP-binding helicase domain that functions as a regulator of transcription. Mutations in this gene result in an array of development defects, including inner ear problems. Mice defective for this gene exhibit many of the clinical features of the CHARGE syndrome caused by mutations in the homologous gene in human. [provided by RefSeq, Sep 2015] |
Documents
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Resources
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| KN303251 | Chd7 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN303251BN | Chd7 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN303251RB | Chd7 - mouse gene knockout kit via CRISPR, HDR mediated | 1 657,00 EUR | |
| KN503251 | Chd7 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 657,00 EUR | |
| GA216568 | Chd7 CRISPRa kit - CRISPR gene activation of mouse chromodomain helicase DNA binding protein 7 | 1 657,00 EUR |